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AI-driven platform for life sciences research and discovery

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Explore, test, and deploy AI models and agents

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Integrate advanced simulation and AI into complex 3D workflows

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Guide for using NVIDIA NGC private registry with GPU cloud

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    Clara for Genomics

    Power unprecedented speed and accuracy in precision genomics with the NVIDIA Clara™ for Genomics software suite.

    Fast, Accurate, and Scalable Solutions for Bioinformatics Workflows

    NVIDIA Parabricks

    Accelerate Genomics Analysis

    NVIDIA® Parabricks® is a scalable genomics software suite for secondary analysis that provides GPU-accelerated versions of trusted, open-source tools.

    Compatible with leading sequencing instruments, researchers, bioinformaticians, and data scientists can use Parabricks across diverse bioinformatics workflows.

    Parabricks increases speed with faster runtimes and reduces cost—while enhancing accuracy and ensuring transparency. As a result, researchers can uncover biological insights and discoveries faster.

    Get Started
    NVIDIA Parabricks: Accelerated genomics analysis
    NVIDIA AI Blueprints

    NVIDIA AI Blueprints

    Easily Deploy Genomics and Single-Cell Solutions

    NVIDIA AI Blueprints are lightweight, easily deployable blueprints for genomics and single-cell analysis.

    Built for bioinformaticians and genomics platform providers, AI Blueprints allow users to easily deploy and test NVIDIA Parabricks and NVIDIA RAPIDS™—including RAPIDS-single-cell developed by scverse—without requiring GPUs or cloud provisions. 

    By easily evaluating and expanding the accessibility of accelerated genomics libraries, scientists and researchers can further genomic understanding by getting up and running faster.

    Try it for Free

    NVIDIA NIM Microservices

    Optimize Alignment and Variant Calling

    NVIDIA NIM™ microservices are production-ready, optimized, and composable microservices with FQ2BAM for alignment and DeepVariant for universal variant calling.

    Data scientists and developers can gain access to the latest advances in generative AI with industry-standard APIs that make it easy to create and deploy cloud-native applications.

    Reduce time-consuming analysis. For alignment, production-ready, industry-standard alignment occurs in minutes instead of hours. Plus, optimize performance of variant calling from different sequencing platforms.

    Try it for Free
     Explore NVIDIA NIM Microservices

    Why Clara for Genomics?

    For Enterprise

    Substantially reduce time to discovery and treatment identification with optimized workflows.

    For IT

    Transform time-consuming analysis from days to minutes to revolutionize the speed, accuracy, and throughput of genomic workflows.

    For Developer

    Optimize the alignment, processing, and variant calling of whole genomes and exomes for both germline and somatic workflows.

    Accelerate Genomic Analysis From End to End

    The genomics market encompasses various methods that cover wide-ranging applications across drug discovery, precision medicine, population health studies, and clinical diagnostics. The landscape is diverse, and includes research institutions, healthcare facilities, sequencing diagnostic centers, national programs, pharmaceuticals, and techbios—all of which play an essential role in genomics discoveries. Faster analysis leads to quicker diagnosis, personalized treatments, and streamlined drug discovery, saving time and resources while improving patient care and enabling real-time, data-driven decisions.

    1. Short-Read Analysis
    2. Long-Read Analysis
    3. Single-Cell
    4. Spatial Omics

    Accelerated Short-Read Analysis

    Short-read sequencing generates short DNA sequences and is valued for its speed and affordability. NVIDIA® Parabricks® accelerates gold-standard secondary analysis tools, from alignment through variant calling, enabling rapid analysis of short-read sequencing data. These tools can be used with data from Element, Illumina, MGI, Singular, and Thermo Fisher.

    Accelerated Short-Read Analysis

    Accelerated Long-Read Analysis

    Long-read sequencing is instrumental in identifying structural variants and can be used to assemble genomes from multiple samples, which can drive the study of genetic diversity in populations. NVIDIA Parabricks accelerates gold-standard secondary analysis tools for basecalling, alignment, and variant calling, enabling rapid analysis of long-read sequencing data. These tools can be used on data from Oxford Nanopore and PacBio long-read sequencers.

    Accelerated Long-Read Analysis

    Single-Cell

    NVIDIA RAPIDS™ accelerates single-cell workflows for data processing and visualization, with a similar usability model as scverse Python libraries. cunnData provides a minimized, lightweight version of the AnnData object for the GPU, enabling rapid data manipulation and processing, which RAPIDS cuGraph and cuML libraries can then analyze downstream.

    Single Cell

    Spatial Omics

    NVIDIA Parabricks includes a single-cell and spatial workflow to accelerate bottlenecks and increase accuracy. Generative AI is specifically applied to spatial analysis with VISTA-2D, a cell imaging foundation model for high-accuracy segmentation. As a deep learning algorithm based on transformers, VISTA-2D works on multiple types of cells and supports multiple datasets, modalities, and GPUs.

    Spatial Omics

    Additional Technologies

    NVIDIA RAPIDS, An open-source suite of GPU-accelerated data science and AI libraries

    NVIDIA RAPIDS

    NVIDIA RAPIDS is an open-source suite of GPU-accelerated data science and AI libraries that improves performance across data pipelines.

    Learn More About RAPIDS
    The software platform for production AI

    NVIDIA AI Enterprise

    NVIDIA AI Enterprise is a software platform for customers who need support for Parabricks in clinical workflows, large sequencing projects, and high-throughput platforms.

    Learn More About AI Enterprise

    Build With NVIDIA Parabricks

    NVIDIA Parabricks provides GPU-accelerated versions of tools used every day by computational biologists and bioinformaticians—enabling significantly faster runtimes, workflow scalability, and lower compute costs. It is available as a public container on NVIDIA NGC™ for use on premises or on any cloud service platform or provider.

    Get Started With NVIDIA Parabricks
     NVIDIA Parabricks

    NVIDIA AI Enterprise

    For customers who need support for Parabricks in clinical workflows, large sequencing projects, high-throughput platforms, or other workflows that require immediate assistance, NVIDIA offers NVIDIA AI Enterprise.

    Compare the benefits of Parabricks with NVIDIA AI Enterprise

    Learn More

    Success Stories

    Spatial Transcriptomics Transforming Healthcare

    Spatial Transcriptomics Transforming Healthcare

    Four Leaders are Advancing Disease Research and Prevention

    Read Industry Brief
    Improving Instrument Speed and Accuracy With NVIDIA Accelerated Computing

    PacBio

    Boosting the Accuracy and Speed of Long-Read Sequencing With Pacific Biosciences.

    Read Case Study
    Multi-omics sequencing created new computational challenges Using NVIDIA RAPIDS

    TGEN

    Reducing Single-Cell and Spatial Analysis From Hours to Minutes With Translational Genomics Research Institute.

    Read Case Study
    The Francis Crick Institute

    The Francis Crick Institute

    Saving Nine Years of Processing Time With NVIDIA Parabricks

    Read Case Study

    Get Started

    Documentation

    Find a collection of documents, guides, manuals, how-tos, and other informational resources in the Parabricks Documentation Hub.

    On-Demand Training
    Documentation Hub

    Platform Updates

    Get notified of new releases, bug fixes, critical security updates, and more for genomics.

    Subscribe

    Contact Us

    Got questions? Our healthcare experts are here to assist you!

    Contact Us

    Get Started

    Documentation

    Find a collection of documents, guides, manuals, how-tos, and other informational resources in the Parabricks Documentation Hub.

    Documentation Hub

    Platform Updates

    Get notified of new releases, bug fixes, critical security updates, and more for genomics.

    Subscribe

    Contact Us

    Got questions? Our healthcare experts are here to assist you!

    Contact Us

    FAQ

    NVIDIA Parabricks is a GPU-accelerated software suite for secondary genomic analysis. Parabricks is compatible with all leading sequencing instruments and supports diverse bioinformatics workflows.

    Parabricks increases speed, reduces cost, and boosts accuracy for secondary genomic analysis.

    1. Increase speed: Experience 135x faster analysis of whole-genome sequencing (WGS) compared to CPU-only solutions.
    2. Reduce cost: Lower compute cost by up to 50% for WGS compared to CPU-only solutions.
    3. Enhance accuracy: Deploy high-accuracy deep learning for all major sequencers.
    4. Ensure transparency: Reproduce results from trusted, open-source tools.

    Parabricks is available as a public container on NVIDIA NGC™ for use on premises or on any cloud service platform or provider. 

    For customers who need support for Parabricks in clinical workflows, large sequencing projects, high-throughput platforms, or other workflows that require immediate assistance, NVIDIA offers NVIDIA AI Enterprise.

    Parabricks can be run on public cloud providers, platforms and partners, and on premises.

    1. Public cloud providers: AWS, Google Cloud, Oracle Cloud, Microsoft Azure, Naver Cloud Platform, Baidu AI Cloud, and Alibaba Cloud
    2. Platforms and partners: DNAnexus, Seqera, AWS HealthOmics, Terra, Velsera, FormBio, and Lifebit
    3. On premises: NVIDIA DGX™ systems, NVIDIA-Certified servers, Dell Technologies, Hewlett Packard Enterprise, Lenovo, Cisco, Atos, and Supermicro

    Parabricks matches the accuracy of open-source tools, so you can switch out open-source tools and get the same results with Parabricks. However, Parabricks also accelerates these tools so you can run analysis even faster. The latest speed benchmarks can be found in the table below.

    NVIDIA RTX PROTM 6000 Newest Support NVIDIA H100 SXM GPU NVIDIA L4 GPU Lowest Cost Per Sample
    2 GPUs 4 GPUs 2 GPUs 4 GPUs 2 GPUs 4 GPUs
    Giraffe(Paired-End) 59.37 31.05 60.10 37.68 81.43 44.57
    DeepSomatic 43.28 23.93 54.32 35.13 215.33 110.05
    Fq2bam(BWA-MEM) 9.02 6.52 10.10 7.28 35.10 19.28
    rna_fq2bam(STAR) 7.55 7.03 7.78 10.23 22.28 12.73
    fq2bam_meth(BWA-Meth) 32.27 22.13 34.60 20.35 132.43 67.03
    DeepVariant 4.67 2.75 7.60 5.90 13.83 8.03
    HaplotypeCaller 8.33 3.83 8.63 4.17 14.20 7.03
    Mutect2 29.50 13.52 27.67 13.67 50.91 26.63

    The latest benchmarks on the most popular NVIDIA GPUs for the newest support, fastest speed, and lowest cost per sample.
    Performance time listed in minutes.

    Parabricks is available as a docker image and can run on premise or in any cloud environment where NVIDIA GPUs are available. Parabricks produces equivalent results to common open-source tools, so it can be used as a drop-in replacement to accelerate key parts of existing workflows. It is also fully configurable, letting users choose which steps and parameter settings to run, and is compatible with leading workflow managers, such as NextFlow and Cromwell.

    Please contact us with your question and check out the developer forum for the latest Parabricks discussions.

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